Author

A. Wiita

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Organism:human· 3 Approach:deep learning· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

A. Barpanda· 2 shared A. Kang· 2 shared C. Kasap· 2 shared E. Ramos· 2 shared H. Geng· 2 shared P. Phojanakong· 2 shared S. Rampersaud· 2 shared V. Steri· 2 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCancer Biology

A. Barpanda

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Author profile →

3 papers

Recent·Most cited

Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR-T cells

C. Kasap, A. Izgutdina, B. Patino-Escobar, A. Kang, N. Chilakapati, N. Akagi, H. Johnson, T. Rashid, J. Werner, A. Barpanda, H. Geng, Y.-H. T. Lin, S. Rampersaud, D. Gil-Alos, A. Sobh, , A. Wiita

Structure-optimized CD27-based CAR-T cells targeting CD70 show >80-fold improved expansion in vivo and offer a potential therapy for high-risk multiple myeloma patients.

bioRxiv · Feb 24, 2024Cancer Biology

Tumor-wide RNA splicing aberrations generate immunogenic public neoantigens

D. W. Kwok, N. O. Stevers, T. Nejo, L. H. Chen, I. Etxeberria, J. Jung, K. Okada, M. Colton Cove, S. Lakshmanachetty, M. Gallus, A. Barpanda, C. Hong, G. K. L. Chan, S. H. Wu, E. Ramos, , H. Okada

The paper identifies tumor-wide splicing aberrations that generate public neoantigens, enabling T-cell-based immunotherapies targeting intratumoral heterogeneity.

bioRxiv · Oct 19, 2023 · PreprintCancer Biology

Functional multi-omics reveals genetic and pharmacologic regulation of surface CD38 in multiple myeloma

P. Choudhry, C. Kasap, B. Patino Escobar, O. Gugliemini, H. Geng, V. Sarin, A. Kang, A. Kishishita, S. Rampersaud, L. Sarah, Y.-H. T. Lin, N. Paranjape, P. Ramkumar, M. Marcoulis, D. Wang, , A. Wiita

This study uses multi-omics approaches to identify regulators of CD38 surface expression in multiple myeloma and assess the impact of therapies on CD38 levels and signaling.

bioRxiv · Aug 4, 2021 · PreprintCancer Biology