Author

A. Y. Chang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:imaging· 2 Research Focus:clustering· 1

Frequent Co-Authors

W. F. Marshall· 2 shared A. J. Porzucek· 1 shared A. M. Proctor· 1 shared A. M. Schwartz· 1 shared A. S. Brack· 1 shared C. A. Klebanoff· 1 shared C. N. Mores· 1 shared C. Y. Oh· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBiophysics

W. F. Marshall

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Effects of IL2/anti-IL2 antibody complex on chikungunya virus-induced arthritis in a mouse model

S. R. Tritsch, A. J. Porzucek, A. M. Schwartz, A. M. Proctor, R. Amdur, P. S. Latham, G. L. Simon, C. N. Mores, A. Y. Chang

The paper tests the effects of IL2/anti-IL2 antibody complex and anti-IL2 mAb on CHIKV arthritis in mice, finding that the complex increases IL2 and Tregs but also Teffs, while the antibody reduces disease scores by increasing IL2 availability.

bioRxiv · Jan 30, 2023Immunology

Identification of the targets of T cell receptor therapeutic agents and cells by use of a high throughput genetic platform

R. S. Gejman, H. F. Jones, M. G. Klatt, A. Y. Chang, C. Y. Oh, S. S. Chandran, T. Korontsvit, V. Zakahleva, T. Dao, C. A. Klebanoff, D. A. Scheinberg

This study introduces a high-throughput genetic platform to identify on- and off-targets of T cell receptor therapeutic agents using MHC-I ligands.

bioRxiv · Sep 1, 2019Cancer Biology

Dynamics of living cells in a cytomorphological state space

A. Y. Chang, W. F. Marshall

The paper applies equilibrium dynamics formalisms to describe cellular transition dynamics in a cytomorphological state space of mouse embryonic fibroblasts, revealing non-uniform energy landscapes and their response to apoptotic agents.

bioRxiv · Feb 14, 2019Biophysics

Inferring cell state by quantitative motility analysis reveals a dynamic state system and broken detailed balance

J. C. Kimmel, A. Y. Chang, A. S. Brack, W. F. Marshall

The paper develops Heteromotility to analyze cell motility and identifies dynamic motility states in mouse cells, finding broken detailed balance in muscle stem cells.

bioRxiv · Jul 26, 2017Cell Biology