Author

A. S. Brack

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. B. Hwang· 1 shared A. Chareunsouk· 1 shared A. Y. Chang· 1 shared D. Pormislow· 1 shared H. Zhou· 1 shared J. C. Kimmel· 1 shared J. T. Rodgers· 1 shared K. Shen· 1 shared

Activity by Year

2017-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

A. B. Hwang

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3 papers

Recent·Most cited

Spatial Heterogeneity of Delta-Like 4 Within a Multinucleated Niche Cell Maintains Muscle Stem Cell Diversity

S. Eliazer, X. Sun, A. S. Brack

This study shows that a gradient of Dll4 from muscle fibers maintains a continuum of quiescent states in muscle stem cells, preserving their diversity.

bioRxiv · Oct 20, 2020 · PreprintCell Biology

PDH Mediated Mitochondrial Respiration Controls the Speed of Muscle Stem Cell Activation in Muscle Repair and Aging

M. H. Raval, P.-C. Cheng, N. Guardino, S. Ahsan, H. Zhou, R. L. Tiwari, L. Wang, A. Chareunsouk, M. Ederer, A. B. Hwang, M. Ellenberger, R. Pepin, D. Pormislow, K. Shen, A. S. Brack, J. T. Rodgers

This study shows that mitochondrial respiration via PDH controls the speed of muscle stem cell activation, which declines with age, and that restoring PDH activity can improve muscle regeneration in aged mice.

bioRxiv · Feb 14, 2020 · PreprintCell Biology

Inferring cell state by quantitative motility analysis reveals a dynamic state system and broken detailed balance

J. C. Kimmel, A. Y. Chang, A. S. Brack, W. F. Marshall

The paper develops Heteromotility to analyze cell motility and identifies dynamic motility states in mouse cells, finding broken detailed balance in muscle stem cells.

bioRxiv · Jul 26, 2017Cell Biology