Author

A. Zychlinsky Scharff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

M. A. Ingersoll· 2 shared M. Rousseau· 2 shared T. Canton· 2 shared C. J. O. O'Brien· 1 shared D. Cansever· 1 shared D. Duffy· 1 shared E. Antequera· 1 shared H. Zdimerova· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

M. A. Ingersoll

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Author profile →

2 papers

Recent·Most cited

Identification of sex differences in tumor-specific T cell infiltration in bladder tumor-bearing mice treated with BCG immunotherapy

M. Rousseau, C. J. O. O'Brien, E. Antequera, H. Zdimerova, D. Cansever, T. Canton, A. Zychlinsky Scharff, M. A. Ingersoll

This study investigates sex differences in tumor-specific T cell infiltration in bladder cancer models treated with BCG immunotherapy, finding sex-based differences in CD8+ T cell infiltration and exhaustion markers.

bioRxiv · Jun 19, 2020Immunology

Sex differences in IL-17 determine chronicity in male versus female urinary tract infection

A. Zychlinsky Scharff, M. Rousseau, L. Lacerda Mariano, T. Canton, M. Albert, M. Fontes, D. Duffy, M. A. Ingersoll

The paper investigates sex differences in urinary tract infection (UTI) severity, finding that male mice develop chronic infections due to impaired innate immunity, while females exhibit robust IL-17-driven responses that promote bacterial clearance.

bioRxiv · Oct 22, 2018Immunology