M. A. Ingersoll

The paper shows that tissue-resident memory T cells (TRM) are necessary and sufficient for immune memory against recurrent urinary tract infections.

This study identifies the cnf1 gene's role in enhancing host colonization by ST131-H30Rx/C2 E. coli, driving its global spread alongside antibiotic resistance genes.

The paper identifies uterine macrophages as functionally specialised, alternatively activated cells replenished from circulating monocytes, with properties conserved between mice and humans.

This study investigates sex differences in tumor-specific T cell infiltration in bladder cancer models treated with BCG immunotherapy, finding sex-based differences in CD8+ T cell infiltration and exhaustion markers.

This paper demonstrates a method to enhance the immunogenicity of E. coli by encapsulating it in a metal-organic framework, leading to improved antibody production and survival in a mouse model.

The paper identifies two distinct bladder macrophage subsets, shows their differential responses to infection, and demonstrates their impact on immune outcomes.

This study shows that immune responses to bacterial prostatitis do not prevent reinfection, as bacterial burden remains high despite adaptive immune activation.

The paper investigates sex differences in urinary tract infection (UTI) severity, finding that male mice develop chronic infections due to impaired innate immunity, while females exhibit robust IL-17-driven responses that promote bacterial clearance.

This study shows E. faecalis suppresses macrophage NF-κB signaling and promotes polymicrobial CAUTI by enhancing E. coli infection.