High interaction valency ensures cohesion and persistence of a microtubule +TIP body at the plus-end of a single specialized microtubule in yeast
S. M. Meier, A.-M. Farcas, A. Kumar, M. Ijavi, R. T. Bill, J. Stelling, E. R. Dufresne, M. O. Steinmetz, Y. Barral
The paper investigates the Kar9 network in yeast, showing it forms a multivalent, liquid-like condensate at microtubule tips that persists during growth and shrinkage and functions as a mechanical coupling device.
bioRxiv · Sep 13, 2021Cell Biology