Drug screen reveals new potent host-targeted antivirals against Mpox virus
Arjit Vijey Jeyachandran, Anne K. Zaiss, Nikhil Chakravarty, Sneha Singh, Yennifer Delgado, Ramya Paravastu, Nivedha Satheeshkumar, Ephrem Gerald, Aakash Jeysankar, Joshua Thomas, Lilly Fuller, Noella Lee, Cameron Taylor, Shantanu H. Joshi, Mark S. Parcells, , Vaithilingaraja Arumugaswami
The paper identifies potent host-targeted antivirals against Mpox virus through high-throughput screening of a kinase inhibitor library, showing efficacy in vitro and in a mouse model.
bioRxiv · May 2, 2025 · PreprintMicrobiology