Cortical Tonic Inhibition Regulates the Expression of Spike-and-Wave Discharges Associated with Absence Epilepsy.
Kile P. Mangan, Aaron B. Nelson, Steven Petrou, Chiara Cirelli, Mathew V. Jones
This study shows that cortical tonic inhibition regulates spike-and-wave discharges in absence epilepsy by demonstrating that its blockade induces seizures and its rescue suppresses them in a mouse model.
bioRxiv · Jul 17, 2017 · PreprintNeuroscience