Convection-enhanced delivery of dexamethasone in glioma suppresses myeloid inflammation while avoiding systemic toxicities
Nathaniel W. Rolfe, Nicholas B. Dadario, Liang Lei, Anthony Tang, Misha Amini, Damian E Teasley, Nkechime Ifediora, Peter J. Chabot, Nathan J. Winans, Nina T. Yoh, Julia Lynn Furnari, Corina P. Kotidis, Clara H. Stucke, Nivia M Urena, Yanping Sun, , Jeffrey N. Bruce
This paper evaluates convection-enhanced delivery of dexamethasone in glioma models, showing reduced systemic toxicity and suppressed myeloid inflammation.
bioRxiv · Sep 24, 2025 · PreprintCancer Biology