Ashwin Viswanathan

Paired Tumor Biopsies Reveal Spatiotemporal Myeloid Remodeling After Local Chemotherapy in Glioblastoma

This study examines the spatiotemporal myeloid response to chemotherapy in glioblastoma using multiple models, showing chemotherapy-induced genotoxic stress and inflammatory remodeling in myeloid cells.

Electrophysiologically Targeted Biopsies Reveal the Transcriptional Landscape of Focal Epilepsy

This study uses electrophysiologically guided biopsies and single-nucleus RNA sequencing to identify transcriptional differences between seizure focus and ictal penumbra in focal epilepsy.

Convection-enhanced delivery of dexamethasone in glioma suppresses myeloid inflammation while avoiding systemic toxicities

This paper evaluates convection-enhanced delivery of dexamethasone in glioma models, showing reduced systemic toxicity and suppressed myeloid inflammation.

Glioma-Induced Alterations in Excitatory Neurons are Reversed by mTOR Inhibition

This study investigates how mTOR inhibition reverses glioma-induced changes in excitatory neurons, showing effects on mRNA, dendritic spines, and neuronal activity.

Unsupervised Clustering Reveals Spatially Varying Single Neuronal Firing Patterns in the Subthalamic Nucleus of Patients with Parkinson's Disease

This study uses unsupervised clustering to identify distinct neuronal firing patterns in the subthalamic nucleus of Parkinson's disease patients and finds spatial differences in firing activity.