Author

Nkechime Ifediora

Columbia University Irving Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Peter CanolliD· 3 shared Ashwin ViswanathaniD· 2 shared Brian J. A. GilliD· 2 shared Clara H. Stucke· 2 shared Colin P. SperringiD· 2 shared Corina P. KotidisiD· 2 shared Damian E TeasleyiD· 2 shared Jeffrey N. BruceiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Peter CanollORCID

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Author profile →

3 papers

Recent·Most cited

Paired Tumor Biopsies Reveal Spatiotemporal Myeloid Remodeling After Local Chemotherapy in Glioblastoma

Anthony J. Tang, Matthew R. Warren, Peter J. Chabot, Damian E Teasley, Nicholas B. Dadario, Angeliki Mela, Misha Amini, Nathaniel W. Rolfe, Michael Argenziano, Colin P. Sperring, Alan X. Chen, Nkechime Ifediora, Ashwin Viswanathan, Melanie Kristt, Athanassios Dovas, , Jeffrey N. Bruce

This study examines the spatiotemporal myeloid response to chemotherapy in glioblastoma using multiple models, showing chemotherapy-induced genotoxic stress and inflammatory remodeling in myeloid cells.

bioRxiv · Jul 15, 2026 · PreprintNeuroscience

High throughput identification of genetic regulators of microglial inflammatory processes in Alzheimer's disease

Christopher L. Cardona, Lai Wei, Joonwon Kim, Ellen Angeles, Gunjandeep Singh, Shiye Chen, Ronak Patel, Nkechime Ifediora, Peter Canoll, Andrew F. Teich, Gunnar Hargus, Alejandro Chavez, Andrew A. Sproul

This study identifies genetic regulators of microglial inflammation in Alzheimer's disease using CRISPRi screens and scRNA-seq, revealing key genes that modulate inflammatory states and disease-relevant clusters.

Journal of Neuroinflammation · Dec 3, 2025Peer-reviewedNeuroscience

Convection-enhanced delivery of dexamethasone in glioma suppresses myeloid inflammation while avoiding systemic toxicities

Nathaniel W. Rolfe, Nicholas B. Dadario, Liang Lei, Anthony Tang, Misha Amini, Damian E Teasley, Nkechime Ifediora, Peter J. Chabot, Nathan J. Winans, Nina T. Yoh, Julia Lynn Furnari, Corina P. Kotidis, Clara H. Stucke, Nivia M Urena, Yanping Sun, , Jeffrey N. Bruce

This paper evaluates convection-enhanced delivery of dexamethasone in glioma models, showing reduced systemic toxicity and suppressed myeloid inflammation.

bioRxiv · Sep 24, 2025 · PreprintCancer Biology