Hippo Signaling Cofactor, WWTR1, at the Crossroads of Human Trophoblast Progenitor Self-Renewal and Differentiation.
Soma S. Ray, Abhik Saha, Ananya Ghosh, Namrata Roy, Ram Parikshan Kumar, Gudrun Meinhardt, Abhirup Mukerjee, Sumedha Gunewardena, Rajnish Kumar, Martin Knöfler, Soumen Paul
This study identifies WWTR1 as a master regulator of human trophoblast progenitor self-renewal and differentiation, showing its role in promoting EVT differentiation and preventing STB fate.
Proceedings of the National Academy of Sciences · Aug 29, 2022Peer-reviewedDevelopmental Biology