Soma S. Ray

This study identifies PRMT1 as a critical regulator of trophoblast development, showing its role in preventing early pregnancy loss through epigenetic control of stemness and differentiation.

The paper investigates the roles of TRIM28, DNA methylation, and p53 in regulating gene and transposon expression in human embryonic and trophoblast stem cells, revealing divergent responses to genomic instability.

The paper shows that parietal trophoblast giant cells regulate hematopoietic stem cell development in the placenta through paracrine signaling.

This study identifies GATA2 and GATA3 as critical regulators of trophoblast progenitor differentiation into syncytiotrophoblasts, essential for placental development and fetal viability.

This study identifies WWTR1 as a master regulator of human trophoblast progenitor self-renewal and differentiation, showing its role in promoting EVT differentiation and preventing STB fate.

This study identifies PKCλ/ι as essential for trophoblast progenitor differentiation into syncytiotrophoblast cells during placentation in both mice and humans.

This study shows that GATA2 and GATA3 in trophoblast giant cells regulate hematopoietic-angiogenic balance in the placenta through paracrine signaling.