Ananya Ghosh

This study shows METTL3 is essential for human placentation by regulating trophoblast self-renewal and differentiation through m6A RNA modifications.

The paper shows that parietal trophoblast giant cells regulate hematopoietic stem cell development in the placenta through paracrine signaling.

This study identifies GATA2 and GATA3 as critical regulators of trophoblast progenitor differentiation into syncytiotrophoblasts, essential for placental development and fetal viability.

This study identifies WWTR1 as a master regulator of human trophoblast progenitor self-renewal and differentiation, showing its role in promoting EVT differentiation and preventing STB fate.

This study identifies PKCλ/ι as essential for trophoblast progenitor differentiation into syncytiotrophoblast cells during placentation in both mice and humans.

This study shows that GATA2 and GATA3 in trophoblast giant cells regulate hematopoietic-angiogenic balance in the placenta through paracrine signaling.