Author

Abigail G. Herrmann

UK Dementia Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Chris-Anne McKenzie· 2 shared Christopher M. HenstridgeiD· 2 shared Colin SmithiD· 2 shared Jamie L. RoseiD· 2 shared Jane TullochiD· 2 shared Makis TziorasiD· 2 shared Rosemary J. JacksoniD· 2 shared Tara L. Spires‐JonesiD· 2 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Chris-Anne McKenzie

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2 papers

Recent·Most cited

Comparative profiling of the synaptic proteome from Alzheimer’s disease patients with focus on the APOE genotype

Raphael Hesse, Maica Llavero Hurtado, Rosemary J. Jackson, Samantha L. Eaton, Abigail G. Herrmann, Martí Colom‐Cadena, Makis Tzioras, Declan King, Jamie L. Rose, Jane Tulloch, Chris-Anne McKenzie, Colin Smith, Christopher M. Henstridge, Douglas J. Lamont, Thomas M. Wishart, Tara L. Spires‐Jones

The paper identifies over 5,500 synaptic proteins in Alzheimer’s disease and controls, revealing APOE4-associated changes in synaptic and mitochondrial function and neuroimmune signaling.

Acta Neuropathologica Communications · Dec 1, 2019Peer-reviewedNeuroscience

Reducing tau ameliorates behavioural and transcriptional deficits in a novel model of Alzheimer’s disease

Eleanor K. Pickett, Abigail G. Herrmann, Jamie McQueen, Kimberly M. Abt, Owen Dando, Jane Tulloch, Pooja Jain, Sophie Louise Dunnett, Sadaf Sohrabi, Maria P. Fjeldstad, Will Calkin, Leo Murison, Rosemary J. Jackson, Makis Tzioras, Anna J. Stevenson, , Tara L. Spires‐Jones

This study shows that reducing tau improves behavioural and transcriptional issues in a mouse model of Alzheimer’s disease, suggesting synaptic tau reduction could be a therapeutic strategy.

bioRxiv · Aug 16, 2018 · PreprintNeuroscience