Loss of SORCS2 is associated with neuronal DNA double-strand breaks
Katerina Gospodinova, Ditte Olsen, Mathias Kaas Ollendorff, Susan Maguire Anderson, Jonathan Phillips, Rosie May Walker, Mairead L. Bermingham, Abigail L. Payne, Panagiotis Giannopoulos, Divya Pandya, Tara L. Spires‐Jones, Catherine M. Abbott, David John Porteous, Simon Glerup, Kathryn Louise Evans
This study shows that loss of SORCS2 increases DNA double-strand breaks in neurons, linking it to neurodegenerative processes.
Cellular and Molecular Neurobiology · Nov 6, 2021Peer-reviewedNeuroscience