Author

Ditte Olsen

Aarhus UniversityORCID 0000-0002-4200-9543Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Mathias Kaas OllendorffiD· 2 shared Simon GlerupiD· 2 shared Abigail L. Payne· 1 shared Amanda Simonsen· 1 shared Anders EtzerodtiD· 1 shared Anna Quattropani· 1 shared Astrid Damgaard Graversen· 1 shared Camilla GustafseniD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

Mathias Kaas OllendorffORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Reshaping the progranulin/sortilin interaction for targeted degradation of extracellular proteins

Camilla Gustafsen, Joachim Vilstrup, Marianne Kristensen, Ditte Køster, Jonas Lende, Casper Larsen, Amanda Simonsen, Astrid Damgaard Graversen, Ditte Olsen, Lone Tjener Pallesen, Christian Bjerggaard Vægter, Jean‐Claude Kresse, Michael Schou, Kathrin Weyer, Anders Etzerodt, , Simon Glerup

This paper develops SORTACs, small molecules that degrade extracellular proteins by hijacking the sortilin/progranulin interaction, showing nanomolar potency against TNFα.

Cell chemical biology · Mar 27, 2026Peer-reviewedBiochemistry

Loss of SORCS2 is associated with neuronal DNA double-strand breaks

Katerina Gospodinova, Ditte Olsen, Mathias Kaas Ollendorff, Susan Maguire Anderson, Jonathan Phillips, Rosie May Walker, Mairead L. Bermingham, Abigail L. Payne, Panagiotis Giannopoulos, Divya Pandya, Tara L. Spires‐Jones, Catherine M. Abbott, David John Porteous, Simon Glerup, Kathryn Louise Evans

This study shows that loss of SORCS2 increases DNA double-strand breaks in neurons, linking it to neurodegenerative processes.

Cellular and Molecular Neurobiology · Nov 6, 2021Peer-reviewedNeuroscience