Lamin B1 Safeguards the B Cell Genome and Shapes Lymphoma Outcome
Filip Filipsky, Katarina B. Chapman, Johannes Bloehdorn, Oscar Maiques, Abigail Lee, Andrew Clear, Jun Wang, John G. Gribben, Michael Hausmann, Christoph Cremer, Andrejs Braun, Marta Crespi Sallan, Tetyana Klymenko
This study shows that Lamin B1 protects B cell genomes by preventing DNA damage and regulating chromatin accessibility, with its loss linked to poor lymphoma outcomes.
HemaSphere · Jun 1, 2026Peer-reviewedCancer Biology