Witnessed trauma exposure induces fear in mice through a reduction in endogenous neurosteroid synthesis
Aidan Evans‐Strong, Najah L. Walton, Katrina L. Blandino, Abigail T. C. Roper, S. Tiffany Donaldson, Michael Lewis, Jamie L. Maguire
This study shows that both direct and witnessed trauma reduce allopregnanolone levels and impair fear regulation in mice, suggesting neurosteroid deficits contribute to PTSD-like behaviors.
Journal of Neuroendocrinology · Mar 14, 2024Peer-reviewedNeuroscience