Aidan Evans‐Strong

This study investigates the role of DRN enkephalin peptides in behavior by knocking them out in mice, finding altered responses to pain, avoidance, and social stimuli.

This study shows that both direct and witnessed trauma reduce allopregnanolone levels and impair fear regulation in mice, suggesting neurosteroid deficits contribute to PTSD-like behaviors.

This study shows that prior positive or negative experiences alter the activity of specific BLA neurons, affecting valence processing by biasing information routing.

This study shows that Sema4D treatment reduces seizure susceptibility and restores benzodiazepine sensitivity in a mouse model of Status Epilepticus.

This study shows chronic stress impairs endogenous neurosteroid signaling in the BLA, leading to behavioral deficits, and suggests targeting neurosteroidogenesis could be a new treatment for mood disorders.