Kalyani Ananthamohan

This study investigates the role of fast skeletal myosin binding protein-C in heart failure, finding that its expression exacerbates cardiac dysfunction and that its deletion improves heart function.

This study investigates the role of fast Myosin Binding Protein-C (fMyBP-C) in skeletal muscle homeostasis across age and disease states using mouse models, finding it critical for muscle function and showing its potential as a therapeutic target.

This study identifies VASH1 and HYAL1 as potential mediators of cardiovascular target organ injury in youth with high blood pressure using multi-omics profiling.

This study identifies miR-27a as a regulator of Hmgcr and cholesterol biosynthesis, showing its role in modulating plasma cholesterol levels in mice.

This study identifies a SNP in the MMP7 promoter that increases hypertension risk by enhancing CREB binding and MMP7 expression under stress conditions.