MEF2C hypofunction in neuronal and neuroimmune populations cooperate to produce MEF2C haploinsufficiency syndrome-like behaviors in mice
Adam J. Harrington, Catherine Bridges, Kayla Blankenship, Ahlem Assali, Stefano Berto, Benjamin M. Siemsen, Hannah Warren Moore, Jennifer Y. Cho, Evgeny Tsvetkov, Acadia M Thielking, Geneviève Konopka, David B. Everman, Michael D. Scofield, Steven A. Skinner, Christopher W. Cowan
This study shows that MEF2C hypofunction in neuronal and neuroimmune populations causes MCHS-like behaviors in mice, highlighting its role in brain development and function.
bioRxiv · Oct 30, 2019 · PreprintNeuroscience