Evgeny Tsvetkov

This study shows that HDAC5 in the prelimbic prefrontal cortex reduces context-associated cocaine seeking but not sucrose seeking, altering synaptic gene expression and excitatory/inhibitory balance.

This study shows that NPAS4 in the medial prefrontal cortex is required for chronic social defeat stress-induced anhedonia and dendritic spine loss, but not social avoidance or anxiety-like behavior.

This study shows NPAS4 regulates drug-cue associations and relapse-like behavior by controlling the activation balance between D1- and D2-MSNs in the nucleus accumbens.

This study shows that chronic methamphetamine exposure in rats causes cognitive deficits by increasing inhibitory synaptic transmission in the prefrontal cortex, which can be mitigated by reducing parvalbumin-positive interneuron activity.

This study shows that MEF2C hypofunction in neuronal and neuroimmune populations causes MCHS-like behaviors in mice, highlighting its role in brain development and function.