Ahlem Assali

Point contact-restricted cAMP signaling controls ephrin-A5-induced axon repulsion

This study shows that point contact-restricted cAMP signals modulate ephrin-A5-induced axon repulsion by controlling Focal Adhesion Kinase phosphorylation and point contact dynamics.

EphB1 controls proper long-range cortical axon guidance through a cell non-autonomous role in GABAergic cells

This study shows that EphB1 in GABAergic neurons is essential for guiding cortical glutamatergic axons during brain development by preventing them from following blood vessels.

NPAS4 in the medial prefrontal cortex mediates chronic social defeat stress- induced anhedonia and dendritic spine loss

This study shows that NPAS4 in the medial prefrontal cortex is required for chronic social defeat stress-induced anhedonia and dendritic spine loss, but not social avoidance or anxiety-like behavior.

Chronic methamphetamine administration produces cognitive deficits through augmentation of GABAergic synaptic transmission in the prefrontal cortex

This study shows that chronic methamphetamine exposure in rats causes cognitive deficits by increasing inhibitory synaptic transmission in the prefrontal cortex, which can be mitigated by reducing parvalbumin-positive interneuron activity.

MEF2C hypofunction in neuronal and neuroimmune populations cooperate to produce MEF2C haploinsufficiency syndrome-like behaviors in mice

This study shows that MEF2C hypofunction in neuronal and neuroimmune populations causes MCHS-like behaviors in mice, highlighting its role in brain development and function.