Developmental BiologyDevelopmental CellPeer-reviewed
PI3K/AKT signalling orchestrates ICM maturation and proper epiblast and primitive endoderm specification
Anna Geiselmann, Adèle Micouin, Sandrine Vandormael‐Pournin…·Michel Cohen‐Tannoudji
This study identifies PI3K/AKT signaling as an upstream regulator that enables ICM formation and specifies both epiblast and primitive endoderm lineages in mouse embryos.
21 citations