A peptide-based screen for cell death inhibitors identifies the cytoprotective compound CDL36
Zintis Inde, Sebastian Keppler, Jesse D. Gelles, Cameron Fraser, Adam Presser, Jarvier N. Mohammed, May Jung, David S. Garvey, Tudor Moldoveanu, Jerry E. Chipuk, Kristopher A. Sarosiek
The paper identifies CDL36, a compound that inhibits cell death by preventing mitochondrial outer membrane permeabilization, with potent cytoprotection against doxorubicin-induced toxicity.
bioRxiv · Jul 10, 2026 · PreprintMolecular Biology