Author
Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Shraddha Subramanian, Peyton C. High, Cara Guernsey-Biddle…·Kendra S. Carmon
This study shows that combining LGR5 and MET-targeting antibody-drug conjugates with different payloads improves efficacy and delays tumor relapse in colorectal cancer models.
Yukimatsu Toh, Jianghua Tu, Ling Wu…·Qingyun J. Liu
The paper develops RSPO2-based peptibody-drug conjugates that target LGR4/5/6 receptors, showing potent anti-tumor activity in colorectal cancer and neuroblastoma models.
Peyton C. High, Zhengdong Liang, Cara Guernsey-Biddle…·Kendra S. Carmon
This study shows cetuximab increases LGR5 expression and improves the efficacy of LGR5-targeting ADCs in colorectal cancer models.
Yukimatsu Toh, Ling Wu, Jianghua Tu…·Qingyun J. Liu
This study develops and tests a camptothecin analog conjugate targeting LGR4/5/6 in CRC models, showing potent anti-tumor activity with minimal toxicity.