Molecular BiologybioRxivPreprint
Identification of chemotherapy targets reveals a nucleus-to-mitochondria ROS sensing pathway
Junbing Zhang, Claire M. Simpson, Jacqueline Berner…·Liron Bar‐Peled
The paper identifies a nucleus-to-mitochondria ROS sensing pathway involving CHK1 and SSBP1 that mediates resistance to platinum-based chemotherapies in ovarian cancers.
DOI 10.1101/2023.03.11.532189