Anthony P. Possemato

This study identifies numerous post-translational modification sites using immunoaffinity enrichment and nDIA mass spectrometry, showing nDIA's superior coverage and efficiency.

The paper introduces Incytr, a method for discovering cell signaling pathways from multi-omics data, demonstrating its application in disease contexts and showing its utility for drug discovery and understanding cell communication.

This study identifies ATM's role in regulating vesicular protein secretion through CHGA and microtubule dynamics via CRMP5 in neurons, linking A-T neural atrophy to growth cone collapse.

The paper identifies a nucleus-to-mitochondria ROS sensing pathway involving CHK1 and SSBP1 that mediates resistance to platinum-based chemotherapies in ovarian cancers.

This study generates craniofacial cartilage organoids from human embryonic stem cells via a neural crest cell intermediate, expressing cartilage markers and growth factors.