ERb limits T cell-mediated inflammation to maintain immune homeostasis
Sarah K McNeer, Alyssia V. Broncano, Sarah J. Stark, Caroline M. Schlessman, Michelle R. Raymond, William B. Tran, Adrian D Kocinski, Nicholas P. Ziats, Wendy A. Goodman
This study shows that ER{beta} in CD4+ T cells suppresses inflammation by limiting proliferation and Th1 polarization, thereby maintaining immune homeostasis.
bioRxiv · Jun 21, 2025 · PreprintImmunology