ZNF121 recruits YTHDF2 to modulate mRNA stability
Giovanni L. Burke, Syed Nabeel‐Shah, Shuye Pu, Nujhat Ahmed, Shahir M. Morcos, James D. Burns, Ahmed Abosen, Guoqing Zhong, Eric I. Campos, Jack F. Greenblatt
The paper identifies ZNF121 as a cofactor that enhances YTHDF2-mediated mRNA decay by facilitating its binding to target transcripts, thereby modulating mRNA stability and cell-cycle regulation.
Cell Reports · Sep 22, 2026Peer-reviewedMolecular Biology