Shuye Pu

The paper identifies extensive interactions among C2H2 zinc finger proteins at chromatin loop anchors using ChIP-seq, interactome data, and chromatin interaction maps.

The paper identifies ZNF121 as a cofactor that enhances YTHDF2-mediated mRNA decay by facilitating its binding to target transcripts, thereby modulating mRNA stability and cell-cycle regulation.

This study shows that TDP-43 and FUS are recruited by the R1810me2s-SMN pathway, and their defects affect RNAPII termination and R-loop accumulation, contributing to neurodegenerative disorders.

The paper shows that m6A modification facilitates nuclear retention of mRNAs with intact 5' splice site motifs through interactions with YTHDC1/YTHDC2, ZFC3H1, and U1-70K.

This study identifies ZBTB48 as a regulator of FTO's substrate selectivity by facilitating its binding to m6A/m6Am-containing RNAs, affecting RNA decay and cancer cell growth.

This study identifies SARS-CoV-2 N protein interactions with host proteins and mRNAs, showing it attenuates stress granule formation and alters gene expression.

The paper identifies Znf684 as a C2H2-ZnF protein that interacts with Nxf1 and regulates mRNA export by binding to specific mRNAs.

The paper identifies ACE2 as the only common host dependency for SARS-CoV-2 across multiple cell lines, while other host factors are cell line specific.

The paper identifies RebL1 as an orthologue of human RBBP4/7 in Tetrahymena thermophila, showing its role in epigenetic regulation and oncogenic functions across species.