Design and Application of a μSiM Outer Blood-Retinal Barrier (OBRB) Model as a Drug Development Tool
Kevin C. Ling, Jordan Jones, Gram Hepner, Ahmet Gurcan, Rufaro Gamariel, Andres F. Muriel‐Torres, Meng-Chun Hsu, Mehran Mansouri, Sami Farajollahi, Vinay V. Abhyankar, Ruchira Singh, Danielle S. W. Benoit, James L. McGrath
The paper develops a μSiM-OBRB model to measure drug transport across the outer blood-retinal barrier, showing drug permeability and disease-relevant phenotypes.
bioRxiv · Aug 24, 2026 · PreprintBioengineering