Vinay V. Abhyankar

The paper shows that collagen fiber alignment alone cannot predict cellular contact guidance responses, as migration behavior varies with the second harmonic generation forward-to-backward ratio (F/B) in 3D collagen hydrogels.

The paper develops a μSiM-OBRB model to measure drug transport across the outer blood-retinal barrier, showing drug permeability and disease-relevant phenotypes.

This paper introduces a modular system for real-time assessment of barrier integrity using impedance sensing in microphysiological systems.

This paper develops a tunable PDMS substrate platform to study mechanical loading and cell-substrate interactions in intervertebral disc cells, showing cells align with applied strain and maintain viability.

This study shows that adding physiological flow to a human tendon-on-a-chip model increases endothelial activation and monocyte infiltration, highlighting the role of flow in immune cell interactions during inflammation.