Danielle S. W. Benoit

The paper develops a μSiM-OBRB model to measure drug transport across the outer blood-retinal barrier, showing drug permeability and disease-relevant phenotypes.

This study uses a 3D iPSC retina model to show that acid ceramidase deficiency causes sphingolipid metabolism changes and photoreceptor degeneration in CLN3 disease, with therapeutic potential for rhAC.

This study compares synthetic and recombinant BMP-2-specific affibodies, finding they have similar structure and function but synthetic ones have lower endotoxin levels and higher yield.