Activator-binding domains are required but insufficient for Med15 recruitment to UAS, revealing a critical role for its disordered C-terminus in directing genome targeting
Aileen Cohen, Joshua Bugis, Vladimir Mindel, Gilad Yaakov, Naama Barkai
The paper shows that Med15's activator-binding domains are necessary but not sufficient for UAS recruitment, and its disordered C-terminus is critical for directing genome targeting.
bioRxiv · May 25, 2026 · PreprintGenomics