Author

Aimée-Lee Luco

McGill University Health Centre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Aaron Kleinman· 1 shared Albéna PramatarovaiD· 1 shared Andrea S. PollardiD· 1 shared Anne CamirandiD· 1 shared Anne‐Tounsia Adoum· 1 shared C. Marcelo SergioiD· 1 shared Carolina Medina‐GómeziD· 1 shared Celia Louise GregsoniD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

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10 top collaborators · 36 mutual co-author links

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1 shared paperGenomics

Aaron Kleinman

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2 papers

Recent·Most cited

Vitamin D counters bone invasion by mammary cancer through inhibition of inflammation and epithelial-to-mesenchymal transition

Jiarong Li, Aimée-Lee Luco, Anne Camirand, Richard Kremer

This study shows vitamin D deficiency accelerates bone invasion in mammary cancer by increasing inflammation and epithelial-to-mesenchymal transition, while vitamin D repletion reduces these effects.

bioRxiv · Sep 3, 2026 · PreprintCancer Biology

An Atlas of Human and Murine Genetic Influences on Osteoporosis

John A. Morris, John P. Kemp, Scott E. Youlten, Laetitia Laurent, John G. Logan, Ryan Chau Chia Chai, Nicholas A. Vulpescu, Vincenzo Forgetta, Aaron Kleinman, Sindhu T. Mohanty, C. Marcelo Sergio, Julian M.W. Quinn, Loan Nguyen‐Yamamoto, Aimée-Lee Luco, Jinchu Vijay, , John Brent Richards

This paper identifies 518 genetic loci associated with bone mineral density and fracture risk, validates causal genes in mice, and provides insights for osteoporosis drug development.

Nature Genetics · Dec 17, 2018Peer-reviewedGenomics