Screening channelrhodopsins using robotic intracellularelectrophysiology and single cell sequencing
Samuel M. Ehrlich, Alexandra D. VandeLoo, Mohamed Badawy, Mercedes M. Gonzalez, Max A. Stockslager, Aimei Yang, Sapna Sinha, Shahar Bracha, Demian Park, Benjamin Magondu, Bo Yang, Edward S. Boyden, Craig R. Forest
The paper introduces a method combining robotic electrophysiology and single-cell sequencing to link opsin sequences to their functional properties, demonstrating its efficiency over manual methods.
Journal of Neuroscience Methods · Dec 19, 2025Peer-reviewedNeuroscience