Craig R. Forest

The paper uses protein language models to predict ChrimsonR mutations that enhance photocurrent response, validating two mutations that significantly improve function.

This paper introduces TEIM, a sub-second extracellular impedance measurement method for epithelial cell monolayers, showing improved time resolution and accuracy compared to traditional EIS.

This paper introduces EEIS to measure apical and basolateral membrane properties in epithelial cells, showing it can detect changes in ion permeability and response times in response to drug treatments.

The paper introduces a method combining robotic electrophysiology and single-cell sequencing to link opsin sequences to their functional properties, demonstrating its efficiency over manual methods.

SAMCell automates cell segmentation in microscopy images using a modified Segment Anything Model, achieving high-quality results without requiring annotated data or technical expertise.

This paper introduces a method to measure transepithelial resistance, capacitance, and membrane ratio using electrochemical impedance spectroscopy on epithelial tissues.

The paper examines how Alzheimer's pathology affects PV interneurons and excitatory neurons in different brain regions of hAPP-KI mice, finding regional differences in neuronal excitability.

The paper introduces a method called patch-walking to improve the efficiency of finding synaptic connections by reusing a single patch clamp electrode, resulting in more connections probed per experiment.

The paper identifies a mutation that enhances the sensitivity of a fluorescent voltage indicator, improving its ability to detect both spiking and subthreshold voltage signals in multiple organisms.

This study investigates rapid cortical adaptation during wakefulness in mice, finding that thalamic synchrony and feedforward inhibition play key roles in shaping sensory representations.

This paper develops a motion compensation method for whole-cell patch-clamp recordings in vivo, significantly improving gigaseal and recording yields in the mouse thalamus.

The paper develops a statistical framework to infer monosynaptic connectivity in vivo using extracellular recordings from rodent thalamocortical pathways.