Sapna Sinha

The paper uses protein language models to predict ChrimsonR mutations that enhance photocurrent response, validating two mutations that significantly improve function.

This paper develops a fatigue-resistant myoneural actuator for implantable biohybrid systems, showing 260% increased fatigue resistance compared to native muscles.

The paper introduces a method combining robotic electrophysiology and single-cell sequencing to link opsin sequences to their functional properties, demonstrating its efficiency over manual methods.

The paper designs proteins with reduced T-cell epitopes using deep generative models and policy optimization to improve immune compatibility across MHC Class I alleles.