Author

Samuel M. Ehrlich

Georgia Institute of TechnologyORCID 0000-0002-5772-8639Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein design· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alexandra D. VandeLooiD· 2 shared Benjamin MagonduiD· 2 shared Craig R. ForestiD· 2 shared Edward S. BoydeniD· 2 shared Sapna SinhaiD· 2 shared Aimei Yang· 1 shared Athena J. ChieniD· 1 shared Bo YangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Alexandra D. VandeLooORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Mutation E300 recommended by protein language models gives ChrimsonR amplified photocurrent response

Samuel M. Ehrlich, Alexandra D. VandeLoo, Benjamin Magondu, Athena J. Chien, Sapna Sinha, Edward S. Boyden, Craig R. Forest

The paper uses protein language models to predict ChrimsonR mutations that enhance photocurrent response, validating two mutations that significantly improve function.

Scientific Reports · Sep 8, 2026Peer-reviewedNeuroscience

Screening channelrhodopsins using robotic intracellularelectrophysiology and single cell sequencing

Samuel M. Ehrlich, Alexandra D. VandeLoo, Mohamed Badawy, Mercedes M. Gonzalez, Max A. Stockslager, Aimei Yang, Sapna Sinha, Shahar Bracha, Demian Park, Benjamin Magondu, Bo Yang, Edward S. Boyden, Craig R. Forest

The paper introduces a method combining robotic electrophysiology and single-cell sequencing to link opsin sequences to their functional properties, demonstrating its efficiency over manual methods.

Journal of Neuroscience Methods · Dec 19, 2025Peer-reviewedNeuroscience