An Itch Receptor Drives Melanoma
Naina Gour, Aishwarya Atakkatan, Moloud Akbarzadeh, Hwan Mee Yong, Aishwarya Magesh, Zhiping Wu, Hyunkeun Joo, Yash Chhabra, Junmin Peng, Ashani T. Weeraratna, Mathieu Laplante, Stéphane Lajoie, Xinzhong Dong
This study identifies MRGPRX4 as a melanoma driver that promotes invasion, therapy resistance, and an immunosuppressive tumor microenvironment.
bioRxiv · Sep 20, 2026 · PreprintCancer Biology