Author

Akash Samuel Annie-Mathew

Children's Hospital of Philadelphia

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Bioengineering· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

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A. P. ZakharoviD· 1 shared Guilherme P. F. NaderiD· 1 shared Mohammad DehghanyiD· 1 shared Tom Hu· 1 shared Vivek B. ShenoyiD· 1 shared Vivek SharmaiD· 1 shared

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Recent·Most cited

BioengineeringbioRxivPreprintFeb 8, 2026

Metabolic starvation-induced cell swelling drives solid stress in tumors

Mohammad Dehghany, Vivek Sharma, Akash Samuel Annie-Mathew…·Vivek B. Shenoy

This study identifies metabolic starvation-induced cell swelling as the primary driver of solid stress in tumors, revealing a mechanical basis for genomic instability and treatment resistance.

DOI 10.64898/2026.02.05.704098

humanbulk RNA-seq

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