Author

Tom Hu

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. P. ZakharoviD· 1 shared Akash Samuel Annie-Mathew· 1 shared Amos StemmeriD· 1 shared Amy J. Plotkin· 1 shared Andrew WangiD· 1 shared Beibei RuiD· 1 shared Carlos CaldasiD· 1 shared Chuhan WangiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioengineering

A. P. ZakharovORCID

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Author profile →

2 papers

Recent·Most cited

AI-Driven Spatial Transcriptomics Unlocks Large-Scale Breast Cancer Biomarker Discovery from Histopathology

Eldad David Shulman, Emma M. Campagnolo, Roshan Lodha, Youngmin Chung, Amos Stemmer, Thomas Cantore, Beibei Ru, Tiangen Chang, Sumona Biswas, Saugato Rahman Dhruba, Sumeet Patiyal, Sushant Patkar, Andrew Wang, Ranjan Kumar Barman, Chuhan Wang, , Eytan Ruppin

Path2Space predicts spatial gene expression and tumor microenvironment from histopathology slides, identifying new breast cancer subgroups and improving biomarker prediction.

Cell · May 8, 2026Peer-reviewedCancer Biology

Metabolic starvation-induced cell swelling drives solid stress in tumors

Mohammad Dehghany, Vivek Sharma, Akash Samuel Annie-Mathew, A. P. Zakharov, Tom Hu, Guilherme P. F. Nader, Vivek B. Shenoy

This study identifies metabolic starvation-induced cell swelling as the primary driver of solid stress in tumors, revealing a mechanical basis for genomic instability and treatment resistance.

bioRxiv · Feb 8, 2026 · PreprintBioengineering