Mohammad Dehghany

The paper identifies a membrane-feedback mechanism that converts single-channel mechanosensing into self-organized Piezo1 clusters through density and tension-dependent interactions.

This study identifies metabolic starvation-induced cell swelling as the primary driver of solid stress in tumors, revealing a mechanical basis for genomic instability and treatment resistance.

This study shows that microtubule forces, not the LINC complex, drive nuclear damage in LMNA cardiomyopathy and that disrupting microtubules can rescue cardiac function.