Author

Akira Mabuchi

The University of Tokyo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:variant calling· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Atsushi ToyodaiD· 2 shared Chiharu Tei· 2 shared Daiju KitagawaiD· 2 shared Masamitsu FukuyamaiD· 2 shared Shohei YamamotoiD· 2 shared Shoji HataiD· 2 shared Takumi ChineniD· 2 shared Kei K Ito· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersCell Biology

Atsushi ToyodaORCID

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2 papers

Recent·Most cited

Comprehensive analysis of end-modified long dsDNA donors in CRISPR-mediated endogenous tagging

Rioka Takagi, Shoji Hata, Chiharu Tei, Akira Mabuchi, Ryosuke Anzai, Masamitsu Fukuyama, Shohei Yamamoto, Takumi Chinen, Atsushi Toyoda, Daiju Kitagawa

This study analyzes end-modified long dsDNA donors in CRISPR-mediated endogenous tagging, showing that 5 biotinylation reduces imprecise insertions and enhances HDR efficiency.

bioRxiv · Jun 28, 2024 · PreprintCell Biology

Comparable analysis of multiple DNA double-strand break repair pathways in CRISPR-mediated endogenous tagging

Chiharu Tei, Shoji Hata, Akira Mabuchi, Shotaro Okuda, Kei K Ito, Mariya Genova, Masamitsu Fukuyama, Shohei Yamamoto, Takumi Chinen, Atsushi Toyoda, Daiju Kitagawa

This study analyzes DNA double-strand break repair pathways in CRISPR-mediated gene knock-in, finding that multiple repair mechanisms affect precision and efficiency.

bioRxiv · Jun 28, 2023 · PreprintGenomics