Shoji Hata

The paper identifies AKIP1 as a novel inner scaffold component essential for centriole integrity through functional genomic analysis and imaging.

This study shows that mutating inx-20, a gap junction gene in C. elegans, extends reproductive span without significantly affecting lifespan.

This study identifies three mechanisms that maintain mother-daughter centriole engagement and describe how structural changes enable their disengagement during mitosis.

This study analyzes end-modified long dsDNA donors in CRISPR-mediated endogenous tagging, showing that 5 biotinylation reduces imprecise insertions and enhances HDR efficiency.

This study identifies mitotic vulnerabilities in AML cells induced by therapeutic agents, showing increased cytotoxicity during mitosis compared to S/G2 phase arrest.

This study analyzes DNA double-strand break repair pathways in CRISPR-mediated gene knock-in, finding that multiple repair mechanisms affect precision and efficiency.