Author

Rahul Sharma

University of VirginiaORCID 0000-0002-3115-3523Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Rahul Sharma7 papers · AstraZeneca (United Kingdom)

Biology Disciplines

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Physiology· 2 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Akshata Patne· 2 shared Eleni Markoutsa· 2 shared Kristof WilliamsiD· 2 shared Lei WangiD· 2 shared Liying Fu· 2 shared Ruisheng LiuiD· 2 shared Sanja ArandjeloviciD· 2 shared Shyam S. MohapatraiD· 2 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersPhysiology

Akshata Patne

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Glomerular-Targeted Delivery of Low-Dose Prednisolone Attenuates Established Lupus Nephritis in MRL/lpr Mice.

Kristof Williams, Georgina Agyekum, Akshata Patne, Eleni Markoutsa, David Raj Chellappan, Nathan Hall, Zhi Tian, Nohely Hernandez Soto, Sebastian Cuadrao, Isabella Lozonschi, Liying Fu, Lilliana Haight, Rahul Sharma, Subhra Mohapatra, Lei Wang, , Ruisheng Liu

This study shows that targeted delivery of low-dose prednisolone via collagen IV 3-targeted nanoparticles reduces lupus nephritis in MRL/lpr mice.

bioRxiv · Aug 6, 2026 · PreprintPhysiology

Glomerulus-Targeted Nanotherapy via Collagen IV-α3 Binding Enhances Renal Immunoregulation in Lupus Nephritis

Lei Wang, Eleni Markoutsa, Rajkumar Venkatadri, Rahul Sharma, Carlos Esquivel, Akshata Patne, Jin Wei, Jie Zhang, Kristof Williams, William Lawless, Amtul Muskan, Liying Fu, Karthick Mayilsamy, Subhra Mohapatra, Shyam Mohapatra, Ruisheng Liu

This study develops glomerulus-targeted nanotherapy using collagen IV-α3 binding peptides to improve renal function and reduce inflammation in lupus nephritis.

Clinical Science · Aug 5, 2026Peer-reviewedPhysiology

ELMO1 dependent efferocytosis protects from nephrotoxin induced acute kidney injury

Blandine Baffert, Michal Cholko, Vikram Sabapathy, Pritika Modhukuru, Isaac Heath, Shuqiu Zheng, Jitendra GAUTAM, Kevin Schneider, Lily Silverman, Mark Okusa, Rahul Sharma, Sanja Arandjelovic

This study investigates the role of ELMO1 in acute kidney injury, finding that ELMO1 deficiency increases tissue injury in cisplatin-induced AKI but not in ischemia-reperfusion models.

Cell Death Discovery · May 19, 2026Peer-reviewedPathology

ST2 Signaling Regulates Innate Immune Responses in Kidney Injury

Vikram Sabapathy, Gabrielle Costlow, Saanvi Acharya, Clint M. Upchurch, Oliver B. Pelletier, Bushra Mekhri, Timothy N. J. Bullock, Norbert Leitinger, Sanja Arandjelovic, Rahul Sharma

This study investigates the role of ST2 signaling in innate immune responses during kidney injury, finding that ST2 deletion reduces acute injury but worsens chronic injury.

bioRxiv · Jan 26, 2026 · PreprintImmunology