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Alayna C. Hauke

University of Rochester Medicine

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Approach:experimental assay· 1 Organism:yeast· 1

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Dmitri N. ErmolenkoiD· 1 shared Eric M. PhizickyiD· 1 shared Erin MarcusiD· 1 shared Franziska StegemanniD· 1 shared Justin C. FayiD· 1 shared Nivedita R. IyeriD· 1 shared Sarah M. OstrowskiiD· 1 shared Thareendra De ZoysaiD· 1 shared

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Molecular BiologyPLoS GeneticsPeer-reviewedJan 31, 2024

A connection between the ribosome and two S. pombe tRNA modification mutants subject to rapid tRNA decay

Thareendra De Zoysa, Alayna C. Hauke, Nivedita R. Iyer…·Eric M. Phizicky

This paper shows that mutations in ribosomal protein genes suppress temperature sensitivity in S. pombe tRNA modification mutants by reducing ribosome concentrations, thereby decreasing tRNA demand and GAAC activation.

17 citations

yeastexperimental assay

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