Neuron-specific partial reprogramming in the dentate gyrus impacts mouse behavior and ameliorates age-related decline in memory and learning.
Alba Vílchez-Acosta, María del Carmen Lapo Maza, Alberto Parras, Alejandra Planells, Sara Picó, Gabriela Desdín-Micó, Calida Mrabti, Clémence Branchina, Céline Yacoub Maroun, Yuri Deigin, Alejandro Ocampo
This study shows that partial reprogramming of dentate gyrus neurons in mice improves memory and learning in aged animals.
bioRxiv · Jul 24, 2024 · PreprintNeuroscience